刘国松
教授 博导 教育部长江学者特聘教授 清华大学“百人”计划教授
1978-1982 川北医学院医学学士
1985-1990 美国加州大学洛杉矶分校神经生理专业博士
1990-1991 加州大学洛杉机分校生理科学系神经生理专业博士后
1991-1993 加州大学洛杉机分校生理科学系研究助理教授
1993-1996 斯坦福大学分子生物和细胞生理系神经生理专业博士后
1996-2001 麻省理工学院大脑和认知科学系、生物系助理教授
1996-2005 麻省理工学院Picower学习和记忆中心研究员
2001-2005 麻省理工学院大脑和认知科学系、生物系副教授
2005-至今 德克萨斯大学奥斯汀分校学习与记忆研究中心 兼职正教授
主要研究方向
应用分子生物学、细胞生物学、生物物理学、计算生物学等技术,研究大脑学习与记忆的机理,在此基础之上,研发能够增强学习与记忆和预防及治疗老年性痴呆症的新药
Selected Publications
·Li, Y., Krupa, B., Kang, J.S., Bolshakov, V.Y., and Liu, G. (2009). Glycine Site of NMDA Receptor Serves as a Spatiotemporal Detector of Synaptic Activity Patterns. J Neurophysiol 102, 578-589.
·Wilson, N.R., Ty, M.T., Ingber, D.E., Sur, M., and Liu, G. (2007). Synaptic Reorganization in Scaled Networks of Controlled Size. J Neurosci 27, 13581-13589.
·Wilson NR, Kang JS, Leung T, Varoqui H, Murnick JG, Erickson JD, Liu G: Presynaptic Control of Excitatory Transmission by Vesicular Transporter Expression. J Neurosci 26:6221-6234, 2005
·Dunah AW, Hueske E, Wyszynski M, Hoogenraad CC, Jaworski J, Pak DT, Simonetta A, Liu G, Sheng M: LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses. Nature Neurosci 8:458-467, 2005
·Slutsky I, Sadeghpour S, Li B, Liu G: Enhancement of Synaptic Plasticity through Chronically Reduced Ca2+ Flux during Uncorrelated Activity. Neuron 44:835-849, 2004
·Liu G: Local structural balance and functional interaction of excitatory and inhibitory synapses in hippocampal dendrites. Nature Neurosci 7:373-379, 2004
·Sala C, Piech V, Wilson NR, Passafaro M, Liu G, Sheng M: Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31:115-130, 2001
·Renger JJ, Egles C, Liu G: A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation. Neuron 29:469-484, 2001
·Fan G, Egles C, Sun Y, Minichiello L, Renger JJ, Klein R, Liu G, Jaenisch R: Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities. Nature Neurosci 3:350-357, 2000
·Cottrell JR, Dube GR, Egles C, Liu G: Distribution, density, and clustering of functional glutamate receptors before and after synaptogenesis in hippocampal neurons. J Neurophysiol 84:1573-1587, 2000
·Tang YP, Shimizu E, Dube GR, Rampon C, Kerchner GA, Zhuo M, Liu G, Tsien JZ: Genetic enhancement of learning and memory in mice. Nature 401:63-69, 1999
·Liu G, Choi S, Tsien RW: Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices. Neuron 22:395-409, 1999
·Liu G, Tsien RW: Properties of synaptic transmission at single hippocampal synaptic boutons. Nature 375:404-408, 1995
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