王一国

博士，研究员

教育及工作经历

1997.9－2001.7       曲阜师范大学生命科学学院 学士

2001.9－2007.1       中科院上海生物化学与细胞生物学研究所     博士

2007.8－2012.8       美国索儿克研究所   博士后

2012.8－            bte365正规网站  研究员

科研领域与研究方向

营养感应与能量稳态调控的分子机制

代表性论文

1.    Jinbo Han^#, Erwei Li^#, Liqun Chen, Yuanyuan Zhang, Fangchao Wei, Jieyuan Liu, Haiteng Deng and Yiguo Wang^*. The CREB Coactivator CRTC2 Controls Hepatic Lipid Metabolism by Regulating SREBP1. Nature (2015) 524 (7564): 243-246.

2.    Yiguo Wang, Gang Li, Jason Goode, Jose C. Paz, Kunfu Ouyang, Robert Screaton, Wolfgang H. Fischer, Ju Chen, Ira Tabas and Marc Montminy. InsP3 Receptor Regulates Hepatic Gluconeogenesis in Fasting and Diabetes. Nature (2012) 485 (7396): 128-132.

3.    Yiguo Wang, Hiroshi Inoue, Kim Ravnskjaer, Kristin Viste, Nina Miller, Yi Liu, Susan Hedrick, Liliana Vera, and Marc Montminy. Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc Natl Acad Sci U S A. (2010) 107 (7): 3087-3092.

4.    Yiguo Wang, Liliana Vera, Wolfgang H Fischer, Marc Montminy. The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature (2009) 460 (7254): 534-537.

5.    Yiguo Wang, Dan Du, Longhou Fang, Guang Yang, Chenyi Zhang, Rong Zeng, Axel Ullrich, Friedrich Lottspeich, Zhengjun Chen.  Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling.  The EMBO Journal. (2006) 25, 5058-5070.

联系方式

电话：+86-10-62783209

E-mail: wangyiguo@biomed.tsinghua.edu.cn