刘晓 博士
博士生导师, “青年千人计划”获得者
1994 南京大学生物系 学士
1997 北京大学细胞遗传系 硕士
2005 约翰霍普金斯医学院生物物理系 博士
2011 斯坦福大学发育生物学系 博士后
2012-至今 清华大学 生命科学学院 PI
主要研究领域与方向
实验室主要通过开发和利用高通量实验技术，从功能基因组学和系统生物学角度，主要以线虫神经系统为模型，研究细胞命运决定和进化的分子机制 。
主要论文
- Li, Y., Zhao, D., Horie, T., Chen, G., Bao, H., Chen, S., Liu. W., Horie, R., Liang, T., Dong, B., Feng, Q., Tao, Q., and Liu, X. A Conserved Gene Regulatory Module Specifies Lateral Neural Borders Across Bilaterians (submitted)
- Liu, W., Yu, E., Chen, S., Ma., X., Lu, Y., and Liu, X. (2017). Spatiotemporal expression profiling of long intervening noncoding RNAs in Caenorhabditis elegans. Scientific Reports (revised)
- Wei, X., Xu, Z., Wang, G., Hou, J., Ma., X., Liu, H., Liu., J., Chen, B., Luo, M., Xie, B., Li, R., Ruan, J. and Liu, X. (2017). pBACode: a random-barcode-based high-throughput approach for BAC paired-end sequencing and physical clone mapping. Nucleic Acids Research (accepted)
- Ma, X., Zhan, G., Sleumer, M.C., Chen, S., Liu, W., Zhang, M.Q., and Liu, X. (2016). Analysis of C. elegans muscle transcriptome using trans-splicing-based RNA tagging (SRT). Nucleic Acids Research 44, e156
- Aerni, S.J., Liu, X., Do C.B., Gross, S.S., Nguyen, A., Guo, S.D., Long, F., Peng, H., Kim, S.K. and Batzoglou, S.(2013) Automated cellular annotation for high-resolution images of adult Caenorhabditis elegans. Bioinformatics 29, i18-i26
- Liu, X., Long, F., Peng, H., Aerni, S.J., Jiang, M., Sánchez-Blanco A., Murray. J.I., Preston, E., Mericle, B., Batzoglou, S., Myers, G., and Kim, S.K. (2009). Analysis of cell fate from single-cell gene expression profiles in C. elegans. Cell 139: 623 - 633
- Liu, X., C.K. Lee, N.D. Clarke, and J.D. Lieb (2006) Quantification of chromatin contributions to DNA-binding site utilization. Genome Research 16: 1517 – 1528
- Liu, X., Noll, D.M., Lieb, J.D., and Clarke, N.D. (2005) DIP-chip: Rapid and accurate determination of DNA-binding specificity. Genome Research 15: 421 – 427
联系方式
bte365正规网站，生物技术馆4-213
北京100084，中国
电话: (010)6279-2304
E-mail: xiaoliu@hotmail.com
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